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(R)evolution of Complex Regulatory Systems

Sci Signal. 2010 Jun 22;3(127):eg4.
Linding R

Signaling systems are exciting to study precisely because they are some of the most complex and dynamical systems that we know. The cell needs operational freedom and, thus, many motif-domain interactions might not be "hard-wired" through evolution, but instead may be like the Linux operating system, where symbolic links can point to files without duplication.

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